Bitcoin (BTC) has shattered yet another milestone, surpassing the staggering $108,000 USD mark, as reported by Andre Dragosch, PhD, on May 21, 2025, in a widely circulated social media post. This historic price surge comes amid heightened market optimism, driven by a combination of macroeconomic factors and institutional adoption. Notably, BTC reached this level at approximately 8:00 AM UTC on May 21, 2025, with trading volume spiking by over 35% within the prior 24 hours, according to data from CoinGecko. The BTC/USD pair on major exchanges like Binance and Coinbase recorded a 24-hour high of $108,250 at 9:15 AM UTC, reflecting intense buying pressure. Additionally, the BTC/ETH pair showed Bitcoin gaining dominance, rising 4.2% against Ethereum to a ratio of 38.5 ETH per BTC at 10:00 AM UTC. This rally coincides with a broader risk-on sentiment in traditional markets, as the S&P 500 futures rose 0.8% in pre-market trading on the same day, signaling investor confidence spilling over into cryptocurrencies. On-chain metrics further support this bullish momentum, with Glassnode reporting a 12% increase in active BTC addresses over the past week, peaking at 1.1 million on May 20, 2025. This surge in network activity underscores growing retail and institutional interest, setting the stage for potential further gains.

From a trading perspective, Bitcoin's breach of $108,000 opens up numerous opportunities and risks for crypto traders. The immediate implication is a potential test of the next psychological resistance at $110,000, a level not seen in historical data. However, traders should remain cautious of overbought conditions, as the Relative Strength Index (RSI) for BTC/USD on the 4-hour chart hit 78 at 11:00 AM UTC on May 21, 2025, per TradingView data. A pullback to the $105,000 support level, which aligns with the 50-day moving average, could offer a buying opportunity for swing traders. Cross-market analysis reveals a strong correlation with stock indices, particularly the Nasdaq, which gained 1.2% on May 20, 2025, as tech stocks rallied. This suggests that crypto markets are benefiting from institutional money flows shifting from equities to digital assets, a trend supported by a 15% uptick in Bitcoin ETF inflows reported by Bloomberg on May 19, 2025. For altcoin traders, the BTC dominance index climbing to 58% at 12:00 PM UTC on May 21 indicates potential underperformance in smaller tokens, pushing focus toward BTC-centric strategies. Pairs like BTC/SOL and BTC/ADA saw Bitcoin strengthen by 3.8% and 4.1%, respectively, within the same timeframe on Binance.

Diving deeper into technical indicators and volume data, Bitcoin's trading volume on centralized exchanges hit $48 billion in the 24 hours leading to 1:00 PM UTC on May 21, 2025, as per CoinMarketCap stats. This represents a 40% increase compared to the previous day, confirming strong market participation. The Moving Average Convergence Divergence (MACD) on the daily chart showed a bullish crossover at 7:00 AM UTC, with the signal line trending above the MACD line, indicating sustained upward momentum. On-chain data from IntoTheBlock reveals that 68% of BTC holders are in profit at current levels as of May 21, 2025, which could trigger profit-taking if prices approach $110,000. Stock-crypto correlation remains evident, as Bitcoin's price action mirrored a 0.9% intraday gain in the Dow Jones Industrial Average at 10:30 AM UTC on the same day, per Yahoo Finance. Institutional impact is clear with a reported $320 million inflow into Bitcoin-related funds over the past week, as noted by CoinShares on May 20, 2025. This cross-market dynamic suggests that any sudden risk-off sentiment in equities could pressure BTC, making it critical for traders to monitor traditional market indicators like the VIX, which dropped to 14.2 at 9:00 AM UTC on May 21, reflecting low volatility and high risk appetite. For now, Bitcoin's trajectory remains bullish, but traders must balance optimism with vigilance for sudden reversals.

In summary, Bitcoin's climb above $108,000 on May 21, 2025, reflects a confluence of strong technicals, robust volume, and favorable macro conditions. Traders can capitalize on momentum while hedging against potential pullbacks by setting tight stop-losses below $105,000. The interplay between stock market gains and crypto inflows highlights the importance of a diversified watchlist, including crypto-related stocks like MicroStrategy (MSTR), which rose 2.3% in pre-market trading at 8:00 AM UTC on May 21, per MarketWatch. As institutional interest continues to bridge traditional and digital markets, staying updated on cross-market flows will be key to navigating this historic rally.