According to @BillGates, the United States' decision to withdraw all its funding from Gavi, the Vaccine Alliance, after this year could trigger a significant global health crisis. Gates highlights that since 2000, Gavi has helped vaccinate 1.1 billion children. He cites Gavi's estimates that a US pullout would result in 75 million children missing vaccinations over the next five years, leading to a potential 1.2 million deaths among them. For traders, such a large-scale humanitarian and health crisis could introduce significant geopolitical instability and disrupt global economic sentiment, potentially leading to increased volatility in risk assets like cryptocurrencies and equities as investors may pivot to risk-off strategies.